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Ebooks on agriculture and the applied life sciences from CAB International

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Mononegaviruses of veterinary importance. Volume 2: molecular epidemiology and control.

Book cover for Mononegaviruses of veterinary importance. Volume 2: molecular epidemiology and control.


This book "Mononegaviruses of Veterinary Importance", Volume 2 complements the first volume "Mononegaviruses of Veterinary Importance: Pathobiology and Molecular Diagnosis". This book discusses the epidemiology and control of Mononegaviruses that pose a significant threat to animals in terms of severity and epidemiological risk. It also addresses viruses with zoonotic potential, and many that can ...


Chapter 3 (Page no: 41)

Hendra and Nipah viruses.

Hendra (HeV) and Nipah (NiV) viruses, in the genus Henipavirus, cause severe, often fatal, disease in people as well as in a broad range of mammalian species. These zoonotic paramyxoviruses are harboured by flying foxes in Australia, the Pacific region and southern and South-east Asia, although there is growing evidence that related henipaviruses infect diverse bat species throughout the world. HeV has caused outbreaks of disease in horses, with horse-to-human transmission in seven cases resulting in four human fatalities. NiV has caused an outbreak of widespread disease in pigs and people in Malaysia and Singapore, and human infections in India and Bangladesh; in the latter countries, zoonotic transmission occurs with nearly annual frequency and human-to-human transmission has been observed. A recent outbreak of disease in horses and people in the Philippines, attributed to henipavirus infection, highlights the ongoing threat to human and livestock health posed by this group of viruses. In this chapter, we discuss the distribution of henipaviruses in bat species in the context of documented human and animal disease outbreaks, as well as the continuing threat of zoonotic spillover. The recent release of an equine HeV vaccine represented a momentous advance in henipavirus infection control, and a promising post-exposure monoclonal antibody has also been developed. Despite these developments, challenges to the control of zoonotic henipavirus transmission, case management of people with persistent central nervous system infection and mitigation of disease outbreaks in resource-poor settings remain, as does the largely undefined threat of the emergence of related, novel viruses from bats.

Other chapters from this book

Chapter: 1 (Page no: 1) Bornaviruses. Author(s): Kinnunen, P. M. Wensman, J. J.
Chapter: 2 (Page no: 15) Newcastle disease virus. Author(s): Munir, M.
Chapter: 4 (Page no: 58) Canine distemper virus. Author(s): Techangamsuwan, S. Pratakpiriya, W.
Chapter: 5 (Page no: 71) Peste des petits ruminants virus. Author(s): Shabbir, M. Z. Munir, M.
Chapter: 6 (Page no: 81) Contribution of epidemiological knowledge and control strategies in the eradication of rinderpest virus. Author(s): Brüning-Richardson, A. Parida, S. Banyard, A. C.
Chapter: 7 (Page no: 98) Bovine parainfluenza virus type 3. Author(s): Spilki, F. R.
Chapter: 8 (Page no: 106) Porcine rubulavirus. Author(s): Berg, M. Cuevas-Romero, S. Moreno-López, J.
Chapter: 9 (Page no: 114) Bovine respiratory syncytial virus. Author(s): Dus Santos, M. J. Mozgovoj, M.
Chapter: 10 (Page no: 127) Avian metapneumovirus. Author(s): Cecchinato, M. Ferreira, H. L. Munir, M. Catelli, E.
Chapter: 11 (Page no: 144) Rabies virus. Author(s): Brandão, P. E.
Chapter: 12 (Page no: 156) Filoviruses. Author(s): Bradfute, S. B. Jahrling, P. B. Kuhn, J. H.
Chapter: 13 (Page no: 174) Sea mammal morbilliviruses. Author(s): Rubio-Guerri, C. Sánchez-Vizcaíno, J. M.
Chapter: 14 (Page no: 185) Infectious hematopoietic necrosis virus. Author(s): Dhar, A. K. Robles-Sikisaka, R. Orry, A. Allnutt, F. C. T.

Chapter details

  • Author Affiliation
  • CSIRO Australian Animal Health Laboratory, Geelong, VIC 3220, Australia.
  • Year of Publication
  • 2016
  • ISBN
  • 9781780644172
  • Record Number
  • 20163393368